Sunday, October 11, 2009

Antiperspirant in deodorant...?

my friend told me today that he read somewhere that antiperspirant in deodorant, the aluminum used in it or something, caused cancer...has anyone else heard about this? is it really true?...

Antiperspirant in deodorant...?
There is no conclusive evidence that antiperspirants in deoderant causes cancer. People believe it because it seems like it 'might' be true.





" a carefully-designed epidemiologic study of this issue published in 2002 compared 813 women with breast cancer and 793 women without the disease found no relationship between breast cancer risk and antiperspirant use, deodorant use, or underarm shaving. "





Here is some of the information that you can read about the rumor:





A persistent internet email rumor has suggested that underarm antiperspirants cause breast cancer


http://www.cancer.org/docroot/MED/conten...





Survey Finds Many Americans Believe Unsubstantiated Claims about Cancer


http://www.cancer.org/docroot/MED/conten...





The problems or half truth stems from the fear of aluminum, which is a natural metal found in the earth's crust. Small amounts of aluminum can be found in our oxygen and water. All our food, air, water, and soil contain aluminum. Some consumer products use aluminum based compounds including antacids, astringents, buffered aspirin, food additives, and antiperspirants. Even though aluminum is found naturally in our environment it is not accumulated to a significant extent in most plants or animals. Usually exposure to small amounts of aluminum have no effect on humans. However, aluminum found in large amounts, such as workers exposed to aluminum dust can have lung problems.Some People with kidney disease store aluminum in their bodies which affects their bones.





Studies show aluminum does not cause cancer in animals.
Reply:Not true. This rumor has been around for a longggggggggggg time.
Reply:No, this is not true. I was diagnosed with Breast Cancer when I was 19, and trust me, I asked that question. No worries!! :o)
Reply:not true. hopefully your friend is not like mine, she worries about things like deoderant causing cancer....yet she smokes a pack a day
Reply:Most women with breast cancer have used antipersperant deodorants containing aluminium.





But then so have most women in our society WITHOUT breast cancer.





Aluminium salts can be found in tumours, so it is possible, but no studies have been able to find conclusive evidence one way or the other.





If you are concerned use a deodorant without aluminium, buteven women who have never used aluminium containing deodorants can get breast cancer.
Reply:Snopes.com says it's undetermined
Reply:not true.
Reply:it is NOT true!!! if it caused cancer why would they sell it?
Reply:if that /was/ the case/it /would not/ be/ on the market /i /am sure
Reply:http://jnci.oxfordjournals.org/cgi/conte...


"The rumor that antiperspirant use causes breast cancer continues to circulate the Internet. Although unfounded, there have been no published epidemiologic studies to support or refute this claim. This population-based case– control study investigated a possible relationship between use of products applied for underarm perspiration and the risk for breast cancer in women aged 20–74 years. Case patients (n = 813) were diagnosed between November 1992 and March 1995; control subjects (n = 793) were identified by random digit dialing and were frequency-matched by 5-year age groups. Product use information was obtained during an in-person interview. Odds ratios (ORs) and 95% confidence intervals were estimated by the use of conditional logistic regression. P values were determined with the Wald {chi}2 test. All statistical tests were two-sided. The risk for breast cancer did not increase with any of the following activities: 1) antiperspirant (OR = 0.9; P = .23) or deodorant (OR = 1.2; P = .19) use; 2) product use among subjects who shaved with a blade razor; or 3) application of products within 1 hour of shaving (for antiperspirant, OR = 0.9 and P = .40; for deodorant, OR = 1.2 and P = .16). These findings do not support the hypothesis that antiperspirant use increases the risk for breast cancer."





http://www3.interscience.wiley.com/cgi-b...


Although risk factors are known to include the loss of function of the susceptibility genes BRCA1/BRCA2 and lifetime exposure to oestrogen, the main causative agents in breast cancer remain unaccounted for. It has been suggested recently that underarm cosmetics might be a cause of breast cancer, because these cosmetics contain a variety of chemicals that are applied frequently to an area directly adjacent to the breast. The strongest supporting evidence comes from unexplained clinical observations showing a disproportionately high incidence of breast cancer in the upper outer quadrant of the breast, just the local area to which these cosmetics are applied. A biological basis for breast carcinogenesis could result from the ability of the various constituent chemicals to bind to DNA and to promote growth of the damaged cells. Multidisciplinary research is now needed to study the effect of long-term use of the constituent chemicals of underarm cosmetics, because if there proves to be any link between these cosmetics and breast cancer then there might be options for the prevention of breast cancer





http://www3.interscience.wiley.com/cgi-b...


Darbre has forwarded a hypothesis and called for further work to establish whether or not the use of underarm cosmetics (particularly containing oestrogenic formulants) contributes to the rising incidence of breast cancer. It would seem prudent to conduct this work because the current database is sparse and the effects of long-term low-level exposures to weakly oestrogenic chemicals on human health, particularly their application to the underarm and the risks of breast cancer, are unknown. The role of oestrogens in breast cancer, however, is undisputed





http://www.eurjcancerprev.com/pt/re/ejcp...


Combined habits are likely for this earlier age of diagnosis. In conclusion, underarm shaving with antiperspirant/deodorant use may play a role in breast cancer. It is not clear which of these components are involved. Reviewed literature insinuates absorption of aluminium salts facilitated by dermal barrier disruption. Case-controlled investigations are needed before alternative underarm hygiene habits are suggested.





Can Rumors Cause Cancer?


http://jnci.oxfordjournals.org/cgi/conte...


One rumor claimed that common antiperspirants, used mostly by women, cause breast cancer. Circulated via e-mail, the rumor has been around for months, possibly years. It claims that antiperspirants are the leading cause of breast cancer and that antiperspirants prevent the body from purging toxins that can then deposit in the lymph nodes, where they can produce . .





Chemical Used in Deodorant Found in Breast Cancer Tissue


http://www.ctfa.org.nz/information/antip...


"Scientists are now looking at some of the chemicals in


underarm hygiene products to see if there's any basis for


these concerns. Parabens are one group of chemicals


being studied. These chemicals are used to preserve foods, medicines, and cosmetics,


and they're commonly found in underarm hygiene products.


In past studies done in test tubes and animals, scientists found that parabens behaved


like weak forms of the hormone estrogen. Parabens prompted the growth of breast


cancer cells in test tubes and the growth of uterine cells in mice."





[...]





Conclusion: This very small study found that certain chemicals—called parabens—


used in foods, cosmetics, and medicines were present in samples of breast cancer


tissue. The researchers suggested that these chemicals might make their way into


breast tissue from outside sources and, once there, might accumulate in levels high


enough to trigger the growth of breast cancer cells. But nothing in this study supports


this hypothesis.





http://www.sciencedirect.com/science?_ob...


Aluminium salts are used as the active antiperspirant agent in underarm cosmetics, but the effects of widespread, long term and increasing use remain unknown, especially in relation to the breast, which is a local area of application. Clinical studies showing a disproportionately high incidence of breast cancer in the upper outer quadrant of the breast together with reports of genomic instability in outer quadrants of the breast provide supporting evidence for a role for locally applied cosmetic chemicals in the development of breast cancer. Aluminium is known to have a genotoxic profile, capable of causing both DNA alterations and epigenetic effects, and this would be consistent with a potential role in breast cancer if such effects occurred in breast cells. Oestrogen is a well established influence in breast cancer and its action, dependent on intracellular receptors which function as ligand-activated zinc finger transcription factors, suggests one possible point of interference from aluminium. Results reported here demonstrate that aluminium in the form of aluminium chloride or aluminium chlorhydrate can interfere with the function of oestrogen receptors of MCF7 human breast cancer cells both in terms of ligand binding and in terms of oestrogen-regulated reporter gene expression. This adds aluminium to the increasing list of metals capable of interfering with oestrogen action and termed metalloestrogens. Further studies are now needed to identify the molecular basis of this action, the longer term effects of aluminium exposure and whether aluminium can cause aberrations to other signalling pathways in breast cells. Given the wide exposure of the human population to antiperspirants, it will be important to establish dermal absorption in the local area of the breast and whether long term low level absorption could play a role in the increasing incidence of breast cancer.





http://www.medscape.com/viewarticle/5245...


Feb. 28, 2006 -- Does regular use of antiperspirants increase a woman's risk for developing breast cancer? A researcher in the U.K. says the answer could very well be yes, but experts tell WebMD that there is still little evidence to back up the claim.





The antiperspirant-breast cancer claim has achieved something akin to urban legend status on the Internet and in the popular press, despite that fact that few clinical studies in humans have addressed the issue.





One of the strongest, published in 2002, found no link between antiperspirant or deodorant use and breast cancer risk. Researchers compared usage patterns among roughly 800 breast cancer patients and a similar number of women without the disease.
Reply:I've heard that, too. I like to be safe, so I believe it. It makes sense. Think about it: all the waste in your body is unhealthy for you, right? It has to be excreted. People who are regularly constipated tend to get colon and rectal cancer. But about half of the waste in your body is excreted through your sweat. If you put something on your body that prevents you from sweating, then all that waste is going to pile up right near your sweat glands in the armpits, and, if you're unlucky enough, you'll develop breast cancer (and men can get that, too. Believe me.)



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